Peptide Database

Peptide NameRegenerating islet-derived protein 3-gamma (REG-3-gamma) (Pancreatitis-associated protein 3) (Regenerating islet-derived protein III-gamma) (Reg III-gamma) [Cleaved into: Regenerating islet-derived protein 3-gamma 16.5 kDa form; Regenerating islet-derived protein 3-gamma 15 kDa form]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Binding / Molecular interaction ▸ Carbohydrate-binding peptide ▸ Lectin

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length174 amino acids

Chemical FormulaC853H1303N231O254S14

DescriptionStandard

        MLPRITITIMSWMLLSCLMLLSQVQGEVAKKDAPSSRSSCPKGSRAYGSYCYALFSVSKNWYDADMACQKRPSGHLVSVLSGAEASFLSSMIKSSGNSGQYVWIGLHDPTLGYEPNRGGWEWSNADVMNYINWETNPSSSSGNHCGTLSRASGFLKWRENYCNLELPYVCKFKA
    

Molecular Weight19306.78 Da

Isoelectric Point (pI)8.67

Net Charge (pH 7.0)3.70

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0213

GRAVY Index-0.26

Hydrophobic Moment 0.45

Boman Index0.05

Instability Index40.19

Aliphatic Index 68.97

Aromaticity 0.1149

Extinction Coeff. Reduced 51910.00

Extinction Coeff. Oxidized 52285.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7771.64

LogP -84.17

H-bond Donors 281.0

H-bond Acceptors 275.0

Rotatable Bonds 624.0

Heavy Atoms 1352.0

Ring Count 38.0

Amide Bonds 187.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0159557 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Anti-Gram-positive Lectin Non-hemolytic

TargetListeria monocytogenes (Gram-positive)