Peptide Database

Peptide NameDefensin alpha 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC439H706N124O141S9

DescriptionStandard

        MRTLALLTTLLLVALQAQAGPLQARCDEAAGQEQHGVDNQDVSISFAWDKISALQVSGSTRGLACTCRLVYCQPAEHSVGSCIIGGMGFTYCCSLED
    

Molecular Weight10265.63 Da

Isoelectric Point (pI)4.85

Net Charge (pH 7.0)-4.38

Net Charge (pH 7.4) -4.81

Charge Density (pH 7.0) -0.0451

GRAVY Index0.24

Hydrophobic Moment 0.60

Boman Index0.14

Instability Index35.62

Aliphatic Index 93.61

Aromaticity 0.0515

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4233.30

LogP -49.18

H-bond Donors 153.0

H-bond Acceptors 148.0

Rotatable Bonds 338.0

Heavy Atoms 713.0

Ring Count 10.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0406577 VERIFIED: NO

Provenance & Taxonomy

OrganismSaimiri boliviensis boliviensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence