Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length462 amino acids

Chemical FormulaC2292H3654N580O661S13

DescriptionStandard

        MFLWFVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTETVDPIGKVQYSFTGMQIVNLGLPKSALGLVPDTGVMLSIGNGYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTIAVTNDDTGHPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALCNALQKQICPLVADSIADINPHLKTLNVLAEVDQYAEIEYSMVGSPVISNTSIDLGLKGEFYNIGQHKEPPFSPTPFSFLSQDTDIIYIGVSAFTINSAGFVYNRAGALRLYITDDMIPSGSPIRLNTKTFGTFIPQIEKMYPGLMMKLLVETVKEPLITFEPNNVTVQASSTVTAYAIQPNSTLSPLFVLNLVRLVQTIILLNRIDISLAKSYVGPFQVTSLDNIFTIVLKVAVIPKVNAHLQEGYPLPAIGKMQLVNSRLQVLKDYLLIGTDVQFTG
    

Molecular Weight50327.86 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)2.01

Net Charge (pH 7.4) 1.36

Charge Density (pH 7.0) 0.0044

GRAVY Index0.28

Hydrophobic Moment 0.68

Boman Index0.20

Instability Index26.59

Aliphatic Index 110.91

Aromaticity 0.0844

Extinction Coeff. Reduced 40340.00

Extinction Coeff. Oxidized 40465.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062189 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria