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MYP_163974
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Basic Information
Nigroain-K2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Adverse immune reactivity ▸ Histamine-release modulation
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
31 amino acids
C151H254N42O41S2
Standard
Sequence
SLWETIKNAGKGFILNILDKIRCKVAGGCKT
Physicochemical Analysis
3378.02 Da
9.59
3.44
3.19
0.1109
0.07
0.61
0.06
31.46
103.87
0.0645
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1365.58
-11.93
50.0
47.0
118.0
236.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012153 VERIFIED: YES
Provenance & Taxonomy
Hylarana nigrovittata [Animal]
127021
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-29
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 25923
11.25 μg/mL
MIC
PaperPeptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovitt
RECORD: Rec_0029749 VERIFIED: YES
Provenance & Taxonomy
Rana nigrovittata [Animal]
127021
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus ATCC43300
9.38 μg/mL
MIC
PMID19778602 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778602/
RECORD: Rec_0043888 VERIFIED: YES
Provenance & Taxonomy
Hylarana maosuoensis [Animal]; Hylarana spinulosa [Animal]; Rana nigrovittata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antioxidant Anti-Gram-positive
Staphylococcus aureus
75 μM
MIC
RECORD: Rec_0044340 VERIFIED: YES
Provenance & Taxonomy
Hylarana nigrovittata [Animal]
127021
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-29
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 43300
9.38 μg/mL
MIC
PaperPeptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovitt
RECORD: Rec_0058678 VERIFIED: YES
Provenance & Taxonomy
Hylarana maosuoensis [Animal]; Hylarana spinulosa [Animal]; Rana nigrovittata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antioxidant Anti-Gram-negative
Escherichia coli
75 μM
MIC
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