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MYP_163970
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Basic Information
tuftsin
Anticancer
Antimicrobial
Delivery / Targeting ▸ Drug delivery vehicle ▸ Drug delivery
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Immunomodulation ▸ Immunoregulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Standard
4 amino acids
C21H40N8O6
Standard
Sequence
TKPR
Physicochemical Analysis
500.59 Da
11.00
1.40
1.21
0.3493
-2.67
0.34
-0.99
-30.20
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
249.98
-2.87
9.0
8.0
15.0
35.0
1.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001403 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PMID1711198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1711198/
RECORD: Rec_0077066 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Tuftsin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: sulfonamide; Conjugated small molecule: 2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuransulfonamide
Bio-Activity Profile
Anticancer
A549, HL-60
PaperSolid phase synthesis and biological activity of tuftsin conjugates PMID21425770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21425770/
RECORD: Rec_0127583 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Tuftsin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: glycosyl; Conjugated small molecule: ¦Â-N-Acetylglucosamine
Bio-Activity Profile
-
PaperSynthesis and immunological evaluation of the conjugates composed of a muramyl peptide GMDP and tuftsin. International Journal of Peptide & Protein Research. 1995 Evidence URLhttps://doi.org/10.1111/j.1399-3011.1995.tb01048.x
RECORD: Rec_0163228 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Tuftsin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: 1,4-dihydroxyanthraquinone (quinizarin) derivative
Bio-Activity Profile
Anticancer
A549, HL-60
PaperSolid phase synthesis and biological activity of tuftsin conjugates PMID21425770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21425770/
RECORD: Rec_0228666 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal] [Plant]; Amaranthus hypochondriacus [Plant]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunoregulator
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