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MYP_163928
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Basic Information
Mytilus defensin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
37 amino acids
C170H258N60O46S6
Standard
Sequence
GFGCPNDYPCHRHCKSIPGRAGGYCGGAHRLRCTCYR
Physicochemical Analysis
4070.63 Da
9.15
4.96
4.51
0.1340
-0.71
0.50
-0.17
38.70
26.49
0.1081
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1687.65
-21.35
67.0
60.0
124.0
282.0
10.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0234599 VERIFIED: YES
Provenance & Taxonomy
Mytilus edulis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0240063 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0253389 VERIFIED: YES
Provenance & Taxonomy
Mytilus edulis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Aerococcus viridans
0.6-1.2 μM
MIC
PMID8702979 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8702979/
RECORD: Rec_0268086 VERIFIED: YES
Provenance & Taxonomy
Mytilus edulis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
0.6-1.2 μM
MIC
PMID8702979 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8702979/
RECORD: Rec_0291941 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
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