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MYP_163925
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Basic Information
PB1 (391-400)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Standard
10 amino acids
C51H92N14O14
Standard
Sequence
KIRPLLVEGT
Physicochemical Analysis
1125.36 Da
8.75
0.76
0.56
0.0762
0.17
0.33
0.04
11.28
146.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
461.88
-2.67
16.0
15.0
37.0
79.0
1.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0171914 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperSynthesis and antiviral activity of PB1 component of the influenza A RNA polymerase peptide fragments. Antiviral Res. 2015 Jan;113:4-10. doi: 10.1016/j.antiviral.2014.10.015. PMID: 25446335. PMID25446335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25446335/
RECORD: Rec_0189733 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Influenza A virus(A/California/07/2009 (H1N1)pdm09/):antiviral activity of the peptide in MDCK cells
71±3 μM
ED50
PaperSynthesis and antiviral activity of PB1 component of the influenza A RNA polymerase peptide fragments. Antiviral Res. 2015 Jan;113:4-10. doi: 10.1016/j.antiviral.2014.10.015. PMID: 25446335. PMID25446335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25446335/
RECORD: Rec_0253873 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Replication inhibition
Influenza A virus(A/California/07/2009 (H1N1)pdm09/) | MDCK cells
71±3 μM
ED50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperSynthesis and antiviral activity of PB1 component of the influenza A RNA polymerase peptide fragments. | Matusevich OV, Egorov VV, Gluzdikov IA, Titov MI, Zarubaev VV, Shtro AA, Slita AV, Dukov MI, Shurygina AP, Smirnova TD, Kudryavtsev IV, Vasin AV, Kiselev OI. | Antiviral Res. 2015 Jan;113:4-10. | DOI:10.1016/j.antiviral.2014.10.015 | PMID:25446335 PMID25446335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25446335/