Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC409H651N127O133S12

DescriptionStandard

        MKTFAVAVTVSLLLTFLCVQENSAVPADELRGLEVPTDDGSRTADQETPEESWNCDSAHMRHRRRRRPCRFCCDCCPNESGCGTCCKF
    

Molecular Weight9860.10 Da

Isoelectric Point (pI)5.60

Net Charge (pH 7.0)-2.40

Net Charge (pH 7.4) -2.88

Charge Density (pH 7.0) -0.0273

GRAVY Index-0.44

Hydrophobic Moment 0.66

Boman Index-0.16

Instability Index69.95

Aliphatic Index 53.18

Aromaticity 0.0568

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4196.70

LogP -52.30

H-bond Donors 157.0

H-bond Acceptors 145.0

Rotatable Bonds 320.0

Heavy Atoms 681.0

Ring Count 13.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0372390 VERIFIED: NO

Provenance & Taxonomy

OrganismPoecilia reticulata [Bacterium]

FamilyHepcidin family

Tax ID8081

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic

MethodQualitative functional evidence