‹ ›
MYP_163851
← PREVIOUS NEXT → BACK
Basic Information
gH493-537(derived from HSV-1 H glycoprotein)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
45 amino acids
C224H349N59O57
Standard
Sequence
AAHLIDALYAEFLGGRVLTTPVVHRALFYASAVLRQPFLAGVPSA
Physicochemical Analysis
4780.53 Da
8.64
0.97
0.68
0.0216
0.77
0.47
0.32
58.36
121.56
0.1111
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1799.48
-12.33
63.0
60.0
145.0
340.0
10.0
45.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0018511 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
toxicity against Vero cells up to 500 μM
500 μM
Cytotoxicity
PaperPubMed PMID: 18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
RECORD: Rec_0105687 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
RECORD: Rec_0168111 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
RECORD: Rec_0263473 VERIFIED: YES
Provenance & Taxonomy
Human alphaherpesvirus 1 [Virus]
Virus-derived peptide
10298;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Herpes simplex virus 1 (Virus entry); Vero
250 μM
Plaque assay
PaperPeptides containing membrane-interacting motifs inhibit herpes simplex virus type 1 infectivity. | Galdiero S, Falanga A, Vitiello M, D'Isanto M, Cantisani M, Kampanaraki A, Benedetti E, Browne H, Galdiero M. | Peptides. 2008 | PMID:18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
RECORD: Rec_0347987 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HSV Entry inhibition
Herpes simplex virus type 1(HSV-1) | Vero cells
250 μM
% inhibition
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperPeptides containing membrane-interacting motifs inhibit herpes simplex virus type 1 infectivity. | Galdiero S, Falanga A, Vitiello M, D'Isanto M, Cantisani M, Kampanaraki A, Benedetti E, Browne H, Galdiero M. | Peptides. 2008 Sep;29(9):1461-71. | DOI:10.1016/j.peptides.2008.04.022 | PMID:18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2