Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC304H453N75O107S5

DescriptionStandard

        MSNTQLLEVLGTETFDVQENLFTFDTTDTIVAESNDDPDTRFKSWSFCTPGCAKTGSFNSYCC
    

Molecular Weight7030.61 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-7.52

Net Charge (pH 7.4) -7.81

Charge Density (pH 7.0) -0.1194

GRAVY Index-0.35

Hydrophobic Moment 0.30

Boman Index0.02

Instability Index21.67

Aliphatic Index 47.94

Aromaticity 0.1270

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2955.12

LogP -37.18

H-bond Donors 105.0

H-bond Acceptors 105.0

Rotatable Bonds 225.0

Heavy Atoms 491.0

Ring Count 11.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301222 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus mutans [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence