Peptide Database

Peptide NameApoE (131-162)+(244+272), hEP

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC327H539N101O93S

DescriptionStandard

        EELRVRLASHLRKLRKRLLRDADDLQKRLAVYEEQAQQIRLQAEAFQARLKSWFEPLVEDM
    

Molecular Weight7405.46 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)1.94

Net Charge (pH 7.4) 1.70

Charge Density (pH 7.0) 0.0318

GRAVY Index-0.74

Hydrophobic Moment 0.78

Boman Index-0.30

Instability Index60.51

Aliphatic Index 102.46

Aromaticity 0.0656

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3235.71

LogP -26.05

H-bond Donors 114.0

H-bond Acceptors 97.0

Rotatable Bonds 261.0

Heavy Atoms 522.0

Ring Count 7.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0397603 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetHuman hepatocellular carcinoma Huh-7.5.1 cells

Activity50-60 %

MethodCytotoxicity

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