Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length471 amino acids

Chemical FormulaC2310H3645N581O664S21

DescriptionStandard

        MMYLTLLILPCLAAVTLGSNPGIQVALTNKGLQYGTRVGADLLQTKIETVSIPQVSGSVSLGPLGSVQYALSGMKVVKVNLPLPTVGFSEGTGVKADLSGLNIAVSGRWNTHYHIIRDGGTFDLAVFRIGTASVVKLGSDSKGHLSVSSVKCSSSVGDIQISFHGGASFIFKSFVKYFKPEIQSKIQQNICPLFEESIQDVEKYLAGMKVSFQVTPTLLIDMPLVSPPMVQTSNLNLSFKGEFYDVKQHTEPPFVADPFQLPQQDGFMVSLGMSEFTLNSATFAYFSGGKFQINITDKMIPPESPIHLTTTSFGAFVPQLPQMYPNMQMLFHVYATETPMFSFLPDNVTLSLSASAKAYVIEKNSSLVPVFRLDSNASFSGRFLLEGGKLKGSLMLNNVTLTLGASEVGTFQTGTLQYMLRMAMNVAVLPKVNEKLKAGIPLPAIGHVQWVNSMLKVKKGFVAVATDANVS
    

Molecular Weight50853.51 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)5.19

Net Charge (pH 7.4) 4.43

Charge Density (pH 7.0) 0.0110

GRAVY Index0.22

Hydrophobic Moment 0.70

Boman Index0.20

Instability Index39.67

Aliphatic Index 94.93

Aromaticity 0.0913

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005572 VERIFIED: NO

Provenance & Taxonomy

OrganismAlbula goreensis [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence