Peptide Database

Peptide NameBeta-defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length101 amino acids

Chemical FormulaC493H764N136O131S11

DescriptionStandard

        MHLLACSAHCPQSPALTPQTQLAVKRWAPPAATMRIHYLLLLTFCFLFFQTVPGADLLTGLGHRSDHYKCAKNGGTCHYSSCPLFSKIEGTCYGGRAKCCI
    

Molecular Weight11044.89 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)5.93

Net Charge (pH 7.4) 5.26

Charge Density (pH 7.0) 0.0587

GRAVY Index0.14

Hydrophobic Moment 0.49

Boman Index0.14

Instability Index78.21

Aliphatic Index 77.43

Aromaticity 0.0990

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4168.85

LogP -39.43

H-bond Donors 154.0

H-bond Acceptors 154.0

Rotatable Bonds 346.0

Heavy Atoms 771.0

Ring Count 24.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0388686 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal