Peptide Database

Peptide NamePENK(114-133)

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC96H147N21O38

DescriptionStandard

        VDELYPVEPEEEANGGEILT
    

Molecular Weight2203.31 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-7.25

Net Charge (pH 7.4) -7.47

Charge Density (pH 7.0) -0.3624

GRAVY Index-0.58

Hydrophobic Moment 0.21

Boman Index0.08

Instability Index82.85

Aliphatic Index 92.50

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 943.29

LogP -7.78

H-bond Donors 29.0

H-bond Acceptors 31.0

Rotatable Bonds 70.0

Heavy Atoms 155.0

Ring Count 3.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028445 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyOpioid

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid Analgesic Neuromodulator

RECORD: Rec_0251773 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/