Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC459H710N120O131S8

DescriptionStandard

        MRTLTLLSAFLLVALQAWAEPLHARADEMPAQKQPPADDQNVVIYFGDDSSSLQVPGSTKGLICHCRVLYCLFGEHLGGTCFILGERYPVCCY
    

Molecular Weight10261.79 Da

Isoelectric Point (pI)5.39

Net Charge (pH 7.0)-3.29

Net Charge (pH 7.4) -3.76

Charge Density (pH 7.0) -0.0353

GRAVY Index0.21

Hydrophobic Moment 0.43

Boman Index0.16

Instability Index45.05

Aliphatic Index 94.41

Aromaticity 0.0968

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3946.48

LogP -33.41

H-bond Donors 140.0

H-bond Acceptors 139.0

Rotatable Bonds 325.0

Heavy Atoms 718.0

Ring Count 19.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403758 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9593

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence