Peptide Database

Peptide NamePhoratoxin D

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC178H300N56O56S6

DescriptionStandard

        KSCCPTTTARNIYNTCRFGGGSRPICAKLSGCKIISGTKCD
    

Molecular Weight4313.02 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)5.70

Net Charge (pH 7.4) 5.40

Charge Density (pH 7.0) 0.1390

GRAVY Index-0.23

Hydrophobic Moment 0.64

Boman Index-0.08

Instability Index47.96

Aliphatic Index 52.44

Aromaticity 0.0488

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1825.30

LogP -26.60

H-bond Donors 72.0

H-bond Acceptors 68.0

Rotatable Bonds 142.0

Heavy Atoms 296.0

Ring Count 4.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004802 VERIFIED: NO

Provenance & Taxonomy

OrganismPhoradendron tomentosum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0138820 VERIFIED: YES

Provenance & Taxonomy

OrganismPhoradendron tomentosum [Plant]

FamilyThionin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Anticancer Cytotoxic Toxin

Target10 cancer cell lines