Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length101 amino acids

Chemical FormulaC509H822N148O147S10

DescriptionStandard

        MSVMKPYLMTISILLILVRKTPGGLFRSQYGKRQEPWNPCQLYHGMCRNSCRKNETQYLTCPNRQKCCLKFSVKIARSNNVKNYDPDSNLSVTNTSSYSKI
    

Molecular Weight11687.52 Da

Isoelectric Point (pI)9.80

Net Charge (pH 7.0)11.52

Net Charge (pH 7.4) 11.14

Charge Density (pH 7.0) 0.1141

GRAVY Index-0.57

Hydrophobic Moment 0.58

Boman Index-0.14

Instability Index42.57

Aliphatic Index 69.41

Aromaticity 0.0891

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4850.28

LogP -54.07

H-bond Donors 175.0

H-bond Acceptors 170.0

Rotatable Bonds 390.0

Heavy Atoms 814.0

Ring Count 17.0

Amide Bonds 114.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0119128 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus arctos horribilis [Bacterium]

FamilyDefensin

Tax ID116960

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence