Peptide Database

Peptide NameDNA dC->dU-editing enzyme APOBEC-3G

Function Ontology

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral budding inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length377 amino acids

Chemical FormulaC2022H3019N563O550S22

DescriptionStandard

        MNPQIRNMVEQMEPDIFVYYFNNRPILSGRNTVWLCYEVKTKDPSGPPLDANIFQGKLYPEAKDHPEMKFLHWFRKWRQLHRDQEYEVTWYVSWSPCTRCANSVATFLAEDPKVTLTIFVARLYYFWKPDYQQALRILCQERGGPHATMKIMNYNEFQHCWNEFVDGQGKPFKPRKNLPKHYTLLHATLGELLRHVMDPGTFTSNFNNKPWVSGQRETYLCYKVERSHNDTWVLLNQHRGFLRNQAPDRHGFPKGRHAELCFLDLIPFWKLDDQQYRVTCFTSWSPCFSCAQKMAKFISNNKHVSLCIFAARIYDDQGRCQEGLRTLHRDGAKIAVMNYSEFEYCWDTFVDRQGRPFQPWDGLDEHSQALSGRLRAI
    

Molecular Weight44719.47 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)8.72

Net Charge (pH 7.4) 7.45

Charge Density (pH 7.0) 0.0231

GRAVY Index-0.62

Hydrophobic Moment 0.83

Boman Index-0.08

Instability Index31.36

Aliphatic Index 64.40

Aromaticity 0.1432

Extinction Coeff. Reduced 96830.00

Extinction Coeff. Oxidized 97580.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0259639 VERIFIED: YES

Provenance & Taxonomy

OrganismChlorocebus aethiops [Animal]

FamilyAPOBEC

Tax ID9534

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Thr32, Thr218

Bio-Activity Profile

Function

Antiviral Release inhibition Budding inhibition Anti-HIV-1

TargetHuman immunodeficiency virus type 1(HIV-1)

RECORD: Rec_0376789 VERIFIED: YES