Peptide Database

Peptide NameBeta-insect excitatory toxin Bj-xtrIT

Function Ontology

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC369H561N95O115S9

DescriptionStandard

        KKNGYPLDRNGKTTECSGVNAIAPHYCNSECTKVYYAESGYCCWGACYCFGLEDDKPIGPMKDITKKYCDVQIIPS
    

Molecular Weight8456.55 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.23

Net Charge (pH 7.4) -0.63

Charge Density (pH 7.0) -0.0030

GRAVY Index-0.53

Hydrophobic Moment 0.58

Boman Index-0.02

Instability Index49.76

Aliphatic Index 52.63

Aromaticity 0.1184

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3371.00

LogP -34.77

H-bond Donors 122.0

H-bond Acceptors 125.0

Rotatable Bonds 271.0

Heavy Atoms 588.0

Ring Count 16.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0274545 VERIFIED: YES

Provenance & Taxonomy

OrganismHottentotta judaicus [Animal]

FamilySodium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide16-42; 27-47; 31-49; 43-69

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense