Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 11

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC445H723N135O146S8

DescriptionStandard

        MRTLALLSSLLLLALHAQAQPLGEKDDHVPAQDQPGADVQGMTISFEGDERSTRDASGSKATLVCHCSRTFCQNSYQELGTCTGIPSGTLYRLCCRRG
    

Molecular Weight10556.84 Da

Isoelectric Point (pI)6.24

Net Charge (pH 7.0)-1.28

Net Charge (pH 7.4) -1.76

Charge Density (pH 7.0) -0.0131

GRAVY Index-0.28

Hydrophobic Moment 0.53

Boman Index-0.04

Instability Index35.14

Aliphatic Index 76.73

Aromaticity 0.0408

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4524.33

LogP -57.57

H-bond Donors 164.0

H-bond Acceptors 156.0

Rotatable Bonds 350.0

Heavy Atoms 734.0

Ring Count 11.0

Amide Bonds 105.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0416730 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence