Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC587H925N165O158S9

DescriptionStandard

        MLIILVLELKTYPTHLFPAAGWEVKRCWKDNIGHCRKRCFHVERYKLLCMNKLTCCIPIKEDDGYTKTPPRPVPFEERITVNTNDWDLFSNSPISCWLSSQLRLRSRSRSP
    

Molecular Weight13110.22 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)6.70

Net Charge (pH 7.4) 6.20

Charge Density (pH 7.0) 0.0604

GRAVY Index-0.41

Hydrophobic Moment 0.56

Boman Index-0.09

Instability Index75.52

Aliphatic Index 81.62

Aromaticity 0.0991

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5194.55

LogP -43.53

H-bond Donors 190.0

H-bond Acceptors 177.0

Rotatable Bonds 424.0

Heavy Atoms 919.0

Ring Count 27.0

Amide Bonds 116.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0260496 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Tax ID9689

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal