Peptide Database

Peptide NameApidaecins type 14 [Cleaved into: Apidaecin-2 (Apidaecin II); Apidaecin-1B (Apidaecin IB); Apidaecin-1A (Apidaecin IA)]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length168 amino acids

Chemical FormulaC863H1370N280O230S

DescriptionStandard

        MKNFALAILVVTFVVAVFGNTNLDPPTRPARLRREAKPEAEPGNNRPIYIPQPRPPHPRLRREAEPKAEPGNNRPIYIPQPRPPHPRLRREAESEAEPGNNRPVYIPQPRPPHPRLRREPEAEPGNNRPVYIPQPRPPHPRLRREPEAEPGNNRPVYIPQPRPPHPRI
    

Molecular Weight19379.91 Da

Isoelectric Point (pI)11.29

Net Charge (pH 7.0)12.97

Net Charge (pH 7.4) 12.47

Charge Density (pH 7.0) 0.0772

GRAVY Index-1.28

Hydrophobic Moment 0.54

Boman Index-0.31

Instability Index70.88

Aliphatic Index 60.42

Aromaticity 0.0476

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8038.39

LogP -86.12

H-bond Donors 260.0

H-bond Acceptors 249.0

Rotatable Bonds 579.0

Heavy Atoms 1374.0

Ring Count 55.0

Amide Bonds 185.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0274085 VERIFIED: YES

Provenance & Taxonomy

OrganismApis mellifera [Animal]

FamilyApidaecin

Tax ID7460

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Non-hemolytic

TargetGram-negative bacteria