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MYP_163573
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Basic Information
Florae
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
26 amino acids
C131H228N36O32
Standard
Sequence
GIGAILKVLATGLPTLISWIKNKRKQ
Physicochemical Analysis
2819.43 Da
11.33
4.76
4.55
0.1829
0.31
0.47
0.15
35.58
138.85
0.0385
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1110.67
-7.62
39.0
37.0
97.0
199.0
3.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0111200 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-penetrating peptide
Human erythrocytes
25 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/22328546/ PMID22328546 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22328546/
RECORD: Rec_0168251 VERIFIED: NO
Provenance & Taxonomy
Apis florea [Animal]
Melittin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperMelittin (MEL), (MLT) Evidence URLhttps://www.uniprot.org/uniprotkb/P01504/entry
RECORD: Rec_0178659 VERIFIED: NO
Provenance & Taxonomy
Apis florea [Animal]
Melittin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Cytolytic Toxin Hemolytic
Evidence URLhttps://www.uniprot.org/uniprotkb/P01504/entry
RECORD: Rec_0200694 VERIFIED: NO
Provenance & Taxonomy
Apis florea [Animal]
Melittin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Toxin
RECORD: Rec_0210729 VERIFIED: YES
Provenance & Taxonomy
Apis florea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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