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MYP_163556
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Basic Information
Ascaphin-8 [G8k]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
19 amino acids
C101H172N24O23
Standard
Sequence
GFKDLLKKAAKALVKTVLF
Physicochemical Analysis
2090.59 Da
10.18
3.76
3.55
0.1977
0.55
0.72
0.14
-4.42
128.42
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
774.75
-2.70
27.0
27.0
74.0
148.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0301610 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
11 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/18554256/ PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0309172 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
150 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/18554256/ PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0358374 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
fibroblast-derived cells
5 μM
LC50
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0393158 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HepG2
8 μM
LC50
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0399765 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
fibroblast-derived cells
9 μM
LC50
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
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