Peptide Database

Peptide NameCCL8

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC401H652N104O114S7

DescriptionStandard

        EKLTGPDKAPVTCCFHVLKLKIPLRVLKSYERINNIQCPMEAVVFQTKQGMSLCVDPTQKWVSEYMEILDQKSQILQP
    

Molecular Weight8978.55 Da

Isoelectric Point (pI)8.45

Net Charge (pH 7.0)1.89

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.0242

GRAVY Index-0.20

Hydrophobic Moment 0.75

Boman Index0.00

Instability Index39.69

Aliphatic Index 93.59

Aromaticity 0.0641

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3516.22

LogP -28.28

H-bond Donors 120.0

H-bond Acceptors 124.0

Rotatable Bonds 301.0

Heavy Atoms 626.0

Ring Count 13.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0406294 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Chemotactic Immunomodulatory Signaling peptide

TargetCCR8 (Mouse); CCR1 (Mouse); CCR2 (Mouse)