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MYP_163474
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Basic Information
ASP-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
7 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FTAVXFX
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004710 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis URID 12.1 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
dhb = dehydrobutyrine, X = I/L. *Cefoxitin resistant >8 µg/ml **Vancomycin resistant >32 µg/ml at 5; unspecified non-canonical residue at 7; dhb = dehydrobutyrine, X = I/L. *Cefoxitin resistant >8 µg/ml **Vancomycin resistant >32 µg/ml
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA 22*
32 μg/mL
MIC
PMID28887200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28887200/
RECORD: Rec_0018787 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis URID 12.1 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
dhb = dehydrobutyrine, X = I/L. *Cefoxitin resistant >8 µg/ml **Vancomycin resistant >32 µg/ml at 5; unspecified non-canonical residue at 7; dhb = dehydrobutyrine, X = I/L. *Cefoxitin resistant >8 µg/ml **Vancomycin resistant >32 µg/ml
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. pyogenes
16 μg/mL
MIC
PMID28887200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28887200/
RECORD: Rec_0029500 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis URID 12.1 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
dhb = dehydrobutyrine, X = I/L. *Cefoxitin resistant >8 µg/ml **Vancomycin resistant >32 µg/ml at 5; unspecified non-canonical residue at 7; dhb = dehydrobutyrine, X = I/L. *Cefoxitin resistant >8 µg/ml **Vancomycin resistant >32 µg/ml
Bio-Activity Profile
Hemolytic
human RBCs
256 μg/mL
Hemolysis
PMID28887200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28887200/
RECORD: Rec_0041700 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis URID 12.1 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
dhb = dehydrobutyrine, X = I/L. *Cefoxitin resistant >8 µg/ml **Vancomycin resistant >32 µg/ml at 5; unspecified non-canonical residue at 7; dhb = dehydrobutyrine, X = I/L. *Cefoxitin resistant >8 µg/ml **Vancomycin resistant >32 µg/ml
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA 19*
64 μg/mL
MIC
PMID28887200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28887200/
RECORD: Rec_0042838 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis URID 12.1 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
dhb = dehydrobutyrine, X = I/L. *Cefoxitin resistant >8 µg/ml **Vancomycin resistant >32 µg/ml at 5; unspecified non-canonical residue at 7; dhb = dehydrobutyrine, X = I/L. *Cefoxitin resistant >8 µg/ml **Vancomycin resistant >32 µg/ml
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
E. faecium NCIM 5443
64 μg/mL
MIC
PMID28887200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28887200/
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