Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length473 amino acids

Chemical FormulaC2338H3757N599O661S15

DescriptionStandard

        MFVGCWLALVALIPMTLGINPGVKVKLSSKGIEYGRQLGMALIQKKLKAIKIPDFSGKQKVKPIGSVRYSLTNLKIVDVGLPQSAVVLVPGTGVRLSIGNAFLRLHGNWRVKYLRIIKDSGSFDLNVKDLTITTSIDIKSDETGRPTVNSVNCVAIVGSVSIKFHGGASWLYNLFTKFIDKALRKTLQNQICPLVANAVSDLNSQLKTLNVVAEVDQYAEIEYSMMSSPTVSNSSIDFSLKGEFYNKGKHQEPPFSAAAFSLPPQINNMLYIGLSAFTANSAAFVYNTAGALSLYITDDMIPQGSPIRLNTRTFGTFIPQIAKRFPGLMMKLLVKTVKNPVVTFEPDNVTVQATATVTAYAIQPNTTLSPLFVLNLDSSVSAKVLVSGLRVTGAISLNKMALTLGTSYVGDFQVGSLDSFFQIVFKGVVIPQLNVQLAKGYPLPTLGKMTLVNTQLHVLKDYMLIGTDLQFTA
    

Molecular Weight51314.43 Da

Isoelectric Point (pI)9.65

Net Charge (pH 7.0)17.82

Net Charge (pH 7.4) 17.26

Charge Density (pH 7.0) 0.0377

GRAVY Index0.25

Hydrophobic Moment 0.85

Boman Index0.17

Instability Index24.96

Aliphatic Index 106.70

Aromaticity 0.0846

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37485.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404762 VERIFIED: NO

Provenance & Taxonomy

OrganismCottoperca gobio (Frogmouth) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria