Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC365H600N106O94S9

DescriptionStandard

        MRVLFSILGVLTLLSIVPLARSFLENQDCSKHRHCRMKCKANEYAIRYCEDWTICCRVKKKESKKKKMW
    

Molecular Weight8265.91 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)9.62

Net Charge (pH 7.4) 9.19

Charge Density (pH 7.0) 0.1394

GRAVY Index-0.33

Hydrophobic Moment 0.56

Boman Index-0.16

Instability Index34.02

Aliphatic Index 83.33

Aromaticity 0.0870

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3289.01

LogP -25.69

H-bond Donors 125.0

H-bond Acceptors 115.0

Rotatable Bonds 287.0

Heavy Atoms 574.0

Ring Count 11.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109064 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence