Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC371H610N112O103S7

DescriptionStandard

        MQRLVLLLAVSLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP
    

Molecular Weight8511.96 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)6.45

Net Charge (pH 7.4) 6.12

Charge Density (pH 7.0) 0.0895

GRAVY Index-0.38

Hydrophobic Moment 0.58

Boman Index-0.20

Instability Index48.00

Aliphatic Index 92.08

Aromaticity 0.0833

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3541.00

LogP -32.31

H-bond Donors 134.0

H-bond Acceptors 117.0

Rotatable Bonds 286.0

Heavy Atoms 593.0

Ring Count 10.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141143 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence