Peptide Database

Peptide NameL5K5W1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC71H127N17O12

DescriptionStandard

        WLKKLLKKLLK
    

Molecular Weight1410.87 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.4323

GRAVY Index-0.13

Hydrophobic Moment 0.78

Boman Index-0.13

Instability Index-18.28

Aliphatic Index 177.27

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 500.21

LogP 1.85

H-bond Donors 18.0

H-bond Acceptors 17.0

Rotatable Bonds 53.0

Heavy Atoms 100.0

Ring Count 2.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0332151 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMRSA-TK784

Activity4 μg/mL

MethodMIC

RECORD: Rec_0349201 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetShigella dysenteriae ATCC 9752

Activity2 μg/mL

MethodMIC

PaperStructural characterization of de novo designed L5K5W model peptide isomers with potent antimicrobial and varied hemolytic activities. Molecules. 2013 Jan 11;18(1):859-876. doi: 10.3390/molecules18010859. PMID: 23344198. PMID23344198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23344198/

RECORD: Rec_0399665 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis ATCC 6633

Activity2 μg/mL

MethodMIC

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