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MYP_163373
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor
Standard
24 amino acids
C118H194N30O28
Standard
Sequence
GLFGVLGSIAKHVLPHVVPVIAEK
Physicochemical Analysis
2480.99 Da
8.61
0.94
0.63
0.0390
1.04
0.43
0.45
33.66
150.00
0.0417
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
881.97
-3.71
29.0
31.0
78.0
176.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073964 VERIFIED: NO
Provenance & Taxonomy
Litoria chloris [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://www.uniprot.org/uniprotkb/P81252/entry
RECORD: Rec_0170053 VERIFIED: YES
Provenance & Taxonomy
Litoria chloris [Animal]
Litoria chloris, Australia
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
PMID9516047;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9516047/
RECORD: Rec_0208472 VERIFIED: YES
Provenance & Taxonomy
Litoria chloris [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anticancer
Listeria innocua
25 μg/mL
MIC
PaperNew antibiotic caerin 1 peptides from the skin secretion of the Australian tree frog Litoria chloris. Comparison of the activities of the caerin 1 peptides from the genus Litoria.
RECORD: Rec_0225587 VERIFIED: YES
Provenance & Taxonomy
Litoria chloris [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0234839 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
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