Peptide Database

Peptide NamePTHrP-(1-21)/PTH-(22-34) (human)

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC184H299N61O51

DescriptionStandard

        AVSEHQLLHDKGKSIQDLRRREWLRKKLQDVHNF
    

Molecular Weight4181.72 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)3.06

Net Charge (pH 7.4) 2.71

Charge Density (pH 7.0) 0.0901

GRAVY Index-1.21

Hydrophobic Moment 0.57

Boman Index-0.39

Instability Index70.86

Aliphatic Index 88.82

Aromaticity 0.0588

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1876.45

LogP -17.12

H-bond Donors 66.0

H-bond Acceptors 57.0

Rotatable Bonds 148.0

Heavy Atoms 296.0

Ring Count 6.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040991 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetPTH1 receptor (Human); PTH2 receptor (Rat); PTH2 receptor (Human)