Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC205H329N61O75S5

DescriptionStandard

        MEKVLDLDVQVKANNNSNDSAGDERITSHSLCTPGCAKTGSFNSFCC
    

Molecular Weight5008.49 Da

Isoelectric Point (pI)4.89

Net Charge (pH 7.0)-2.44

Net Charge (pH 7.4) -2.78

Charge Density (pH 7.0) -0.0520

GRAVY Index-0.42

Hydrophobic Moment 0.40

Boman Index-0.07

Instability Index14.99

Aliphatic Index 58.09

Aromaticity 0.0426

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2226.18

LogP -32.75

H-bond Donors 79.0

H-bond Acceptors 79.0

Rotatable Bonds 168.0

Heavy Atoms 346.0

Ring Count 4.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180879 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus aureus [Bacterium]

FamilyLantibiotic

Tax ID1280

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

RECORD: Rec_0218460 VERIFIED: NO