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MYP_163311
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Basic Information
Kn2-7 (BmKn2 peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Wound healing/Regeneration ▸ Wound healing
Standard
13 amino acids
C81H140N24O14
Standard
Sequence
FIKRIARLLRKIF
Physicochemical Analysis
1674.13 Da
12.00
4.76
4.55
0.3660
0.55
1.10
-0.10
36.06
157.69
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
650.26
-1.00
25.0
19.0
59.0
119.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0186232 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID22792229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22792229/
RECORD: Rec_0192640 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa AB93066
25 μg/mL
MIC
PMID22792229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22792229/
RECORD: Rec_0196587 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
90.27 μg/mL
HC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/22792229/ PMID22792229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22792229/
RECORD: Rec_0196916 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Methicillin resistant Staphylococcus aureus
6.25 μg/mL
MIC
PMID22792229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22792229/
RECORD: Rec_0199788 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC29213
5 μg/mL
MIC
PMID34335511 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34335511/
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