Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC369H602N106O96S8

DescriptionStandard

        MRVLHSILGVLALLSIVPQARTSFFKDTCSLETYNCRMKCNADERAIRYCSDWTICCKWRKTKLKKKKKW
    

Molecular Weight8315.90 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)10.53

Net Charge (pH 7.4) 10.15

Charge Density (pH 7.0) 0.1504

GRAVY Index-0.33

Hydrophobic Moment 0.67

Boman Index-0.15

Instability Index4.25

Aliphatic Index 79.43

Aromaticity 0.1000

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3328.61

LogP -27.95

H-bond Donors 128.0

H-bond Acceptors 116.0

Rotatable Bonds 284.0

Heavy Atoms 579.0

Ring Count 12.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296207 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptonychotes weddellii (Weddell seal) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin