Peptide Database

Peptide NameDefensin-like protein 2 (Sa-AFP2; Plant defensin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC242H373N77O69S8

DescriptionStandard

        QKLCQRPSGTWSGVCGNNNACRNQCINLEKARHGSCNYVFPAHKCICYFPC
    

Molecular Weight5721.54 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)4.85

Net Charge (pH 7.4) 4.42

Charge Density (pH 7.0) 0.0952

GRAVY Index-0.46

Hydrophobic Moment 0.43

Boman Index-0.08

Instability Index36.98

Aliphatic Index 47.84

Aromaticity 0.0980

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2375.35

LogP -29.84

H-bond Donors 88.0

H-bond Acceptors 84.0

Rotatable Bonds 182.0

Heavy Atoms 396.0

Ring Count 11.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407620 VERIFIED: YES

Provenance & Taxonomy

OrganismSinapis alba [Plant],Brassica hirta [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetFusarium oxysporum

Activity2.3 μg/mL

MethodIC50

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