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MYP_163303
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Basic Information
Defensin-like protein 2 (Sa-AFP2; Plant defensin)
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
51 amino acids
C242H373N77O69S8
Standard
Sequence
QKLCQRPSGTWSGVCGNNNACRNQCINLEKARHGSCNYVFPAHKCICYFPC
Physicochemical Analysis
5721.54 Da
8.92
4.85
4.42
0.0952
-0.46
0.43
-0.08
36.98
47.84
0.0980
8480.00
8980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2375.35
-29.84
88.0
84.0
182.0
396.0
11.0
59.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0299868 VERIFIED: YES
Provenance & Taxonomy
Sinapis alba [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
Cyclization
4-51, 15-36, 21-45, 25-47
②The residue at position 8 is phosphorylated
Bio-Activity Profile
Antimicrobial Antifungal
Pyricularia oryzae
0.3 μg/mL
MIC
PMID8422949;8836771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0322728 VERIFIED: YES
Provenance & Taxonomy
Sinapis alba [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
None
4-51, 15-36, 21-45, 25-47
②The residue at position 8 is phosphorylated
Bio-Activity Profile
Antimicrobial Antifungal
lycopersici
2.3 μg/mL
MIC
PMID8422949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0326403 VERIFIED: YES
Provenance & Taxonomy
Sinapis alba [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
None
4-51, 15-36, 21-45, 25-47
②The residue at position 8 is phosphorylated
Bio-Activity Profile
Antimicrobial Antifungal
Verticillium dahliae
1.2 μg/mL
MIC
PMID8422949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0340468 VERIFIED: YES
Provenance & Taxonomy
Sinapis alba [Plant],Brassica hirta [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium culmorum
2.3 μg/mL
IC50
PMID8422949;8836771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0342189 VERIFIED: YES
Provenance & Taxonomy
Sinapis alba [Plant],Brassica hirta [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antifungal
Botrytis cinerea
3.5 μg/mL
IC50
PMID8422949;8836771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
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