Peptide Database

Peptide NameAlloferon (6-13)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC34H49N15O10

DescriptionStandard

        HGQHGVHG
    

Molecular Weight827.85 Da

Isoelectric Point (pI)7.02

Net Charge (pH 7.0)0.02

Net Charge (pH 7.4) -0.33

Charge Density (pH 7.0) 0.0027

GRAVY Index-1.26

Hydrophobic Moment 0.29

Boman Index0.06

Instability Index-30.14

Aliphatic Index 36.25

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 396.15

LogP -5.50

H-bond Donors 13.0

H-bond Acceptors 13.0

Rotatable Bonds 25.0

Heavy Atoms 59.0

Ring Count 3.0

Amide Bonds 8.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0427242 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAlloferon

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Entry inhibition

TargetCoxsackie virus B2 (clinical strain) | Hep-2 cells

Activity78 μM

MethodIC50

Half-LifeMammalian: 3.5 h; Yeast: 10 min; E. coli: >10 h

FIRST PREV 1 ... 3 4 5

Showing 1 records on this page Ã‚Â· Page 5 of 5