Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC155H248N48O51S8

DescriptionStandard

        TCSNKGQQCGDDSDCCWHLCCVNNKCAHLILLCNL
    

Molecular Weight3856.44 Da

Isoelectric Point (pI)5.92

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.92

Charge Density (pH 7.0) -0.0430

GRAVY Index-0.01

Hydrophobic Moment 0.39

Boman Index0.02

Instability Index44.13

Aliphatic Index 78.00

Aromaticity 0.0286

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1609.04

LogP -20.73

H-bond Donors 61.0

H-bond Acceptors 60.0

Rotatable Bonds 127.0

Heavy Atoms 262.0

Ring Count 4.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0275599 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic

RECORD: Rec_0410206 VERIFIED: NO

Provenance & Taxonomy

OrganismConus magus,Magician's cone snail [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-16; 9-21; 15-26; 20-33

Bio-Activity Profile

Function

Toxin