Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length245 amino acids

Chemical FormulaC1224H1901N355O372S3

DescriptionStandard

        DKGNPVPHGWHTPPGRDMVRVRKMEWDSSRKAYTFTTEEDPRITIIWTPDGSGVNIPSNTGNQNPVRIPNPVVVDPLPEDTNIEATTSPTLEEKNFADYILILPVSDIPPIYIYLRNNPGQVTDKGQKVSGIWLSDANTGNGSPVPGQIADKLRGRTFENFDQFRKAFWLEVSKYPELSSQFRGSNKIHIRNGNSPFTREQDRAGGRERYEIHHIIPISKGGEVYNVDNMGITSPKRHIDIHSTR
    

Molecular Weight27637.54 Da

Isoelectric Point (pI)7.25

Net Charge (pH 7.0)0.41

Net Charge (pH 7.4) -0.21

Charge Density (pH 7.0) 0.0017

GRAVY Index-0.77

Hydrophobic Moment 0.63

Boman Index-0.10

Instability Index46.56

Aliphatic Index 69.96

Aromaticity 0.0816

Extinction Coeff. Reduced 37930.00

Extinction Coeff. Oxidized 37930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0182472 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia alba [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli