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MYP_163269
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Basic Information
HD5[L16R]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
32 amino acids
C144H245N53O45S6
Standard
Sequence
ATCYCRTGRCATRESRSGVCEISGRLYRLCCR
Physicochemical Analysis
3631.20 Da
9.22
4.74
4.46
0.1481
-0.37
0.81
-0.32
33.54
51.88
0.0625
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1635.16
-22.68
70.0
56.0
120.0
248.0
2.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0194955 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-31, 5-20, 10-30
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 23269800 PMID23269800 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23269800/
RECORD: Rec_0198009 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 59.4%, T 18.8%, C 21.9% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0275141 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-31, 5-20, 10-30
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 23269800 PMID23269800 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23269800/
RECORD: Rec_0292339 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-31, 5-20, 10-30
Bio-Activity Profile
Antimicrobial Antiviral
neutralization activity against HSV-2 during the preinfection stage
67 μg/mL
IC50
PaperPubMed PMID: 23269800 PMID23269800 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23269800/
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