Peptide Database

Peptide Namehepcidin TH1-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC94H153N27O24S8

DescriptionStandard

        AIKCKFCCGCCTPGVCGVCCRF
    

Molecular Weight2301.91 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)2.71

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.1234

GRAVY Index1.11

Hydrophobic Moment 0.31

Boman Index0.22

Instability Index20.50

Aliphatic Index 48.64

Aromaticity 0.0909

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 799.80

LogP -8.82

H-bond Donors 36.0

H-bond Acceptors 35.0

Rotatable Bonds 71.0

Heavy Atoms 153.0

Ring Count 3.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0054610 VERIFIED: YES

Provenance & Taxonomy

OrganismScophthalmus maximus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)