Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC481H767N123O132S8

DescriptionStandard

        MKLFLVLIVLLSQVLTAWAKPPRCFNNVAGYCKKKCKMGEISEMGCLHGKLCGVNEEENKKYHKSHQPPPQSDQKVAEVYDYVIYPTVTLVSIL
    

Molecular Weight10641.50 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)3.72

Net Charge (pH 7.4) 3.24

Charge Density (pH 7.0) 0.0395

GRAVY Index-0.10

Hydrophobic Moment 0.61

Boman Index0.07

Instability Index42.61

Aliphatic Index 93.19

Aromaticity 0.0851

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13200.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4072.94

LogP -30.79

H-bond Donors 141.0

H-bond Acceptors 147.0

Rotatable Bonds 353.0

Heavy Atoms 744.0

Ring Count 18.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0254145 VERIFIED: NO

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence