Peptide Database

Peptide NameCyclotide Viba 15

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC116H185N35O39S6

DescriptionStandard

        CGETCVGGTCNTPGCACSWPVCTRNGLPV
    

Molecular Weight2886.31 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0102

GRAVY Index0.24

Hydrophobic Moment 0.31

Boman Index0.17

Instability Index45.32

Aliphatic Index 46.90

Aromaticity 0.0345

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1154.07

LogP -17.62

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 83.0

Heavy Atoms 196.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145183 VERIFIED: YES

Provenance & Taxonomy

OrganismViola philippica [Plant]

FamilyCyclotide

Tax ID39648

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Cytotoxic

RECORD: Rec_0290491 VERIFIED: NO