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MYP_163187
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Basic Information
Brevinin-1SE
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Adverse immune reactivity ▸ Histamine-release modulation
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
23 amino acids
C111H193N31O26S2
Standard
Sequence
FLPLVRGAAKLIPSVVCAISKRC
Physicochemical Analysis
2442.04 Da
10.11
3.74
3.50
0.1625
1.05
0.67
0.22
28.16
135.65
0.0435
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
902.24
-6.16
34.0
32.0
78.0
170.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0206620 VERIFIED: YES
Provenance & Taxonomy
Lithobates sevosus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Non-hemolytic
Escherichia coli (Gram-negative)
PMID16386333 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16386333/
RECORD: Rec_0298636 VERIFIED: NO
Provenance & Taxonomy
Rana sevosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli and, Mycobacterium luteus
RECORD: Rec_0343328 VERIFIED: YES
Provenance & Taxonomy
Rana sevosa [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli K12
PaperPubMed PMID: 16386333 PMID16386333 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16386333/
RECORD: Rec_0346908 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 21.7%, T 34.8%, C 43.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0403753 VERIFIED: YES
Provenance & Taxonomy
Rana sevosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus NCT C2665
PMID16386333 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16386333/
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