Peptide Database

Peptide NameSLAY-screened peptide P5210

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC83H130N26O30

DescriptionStandard

        SGVHFSPSTRLSGDPNGAVS
    

Molecular Weight1972.08 Da

Isoelectric Point (pI)6.46

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -0.71

Charge Density (pH 7.0) -0.0226

GRAVY Index-0.35

Hydrophobic Moment 0.36

Boman Index0.06

Instability Index24.16

Aliphatic Index 53.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 890.99

LogP -14.94

H-bond Donors 31.0

H-bond Acceptors 31.0

Rotatable Bonds 59.0

Heavy Atoms 139.0

Ring Count 4.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0277949 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/