Peptide Database

Peptide NameLP-M1(Derived from Lausporin-1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC82H130N24O15

DescriptionStandard

        FLRRLWRVAKSLF
    

Molecular Weight1692.06 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2892

GRAVY Index0.30

Hydrophobic Moment 0.93

Boman Index-0.09

Instability Index86.32

Aliphatic Index 120.00

Aromaticity 0.2308

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 660.26

LogP -1.85

H-bond Donors 26.0

H-bond Acceptors 19.0

Rotatable Bonds 55.0

Heavy Atoms 121.0

Ring Count 4.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0278176 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyLausporin-1

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 29213

Activity5 μM

MethodMIC

Paper基于蝎抗菌肽Lausporin-1设计衍生肽以优化其抗“ESKAPE”病原菌活性; Analogues Designed from Scorpion-Derived Peptide Lausporin-1 Exhibit Improved Antimicrobial Activity Against ‘ESKAPE’ Pathogens. [J].湖北医药学院学报,2021,40(05):441-445+453. DOI:10.13819/j.issn.2096-708X.2021.05.001. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37236

RECORD: Rec_0294517 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyLausporin-1

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa ATCC 27853

Activity20 μM

MethodMIC

Paper基于蝎抗菌肽Lausporin-1设计衍生肽以优化其抗“ESKAPE”病原菌活性; Analogues Designed from Scorpion-Derived Peptide Lausporin-1 Exhibit Improved Antimicrobial Activity Against ‘ESKAPE’ Pathogens. [J].湖北医药学院学报,2021,40(05):441-445+453. DOI:10.13819/j.issn.2096-708X.2021.05.001. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37236

RECORD: Rec_0414147 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyLausporin-1

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetKlebsiella pneumoniae ATCC 27853

Activity5 μM

MethodMIC

Paper基于蝎抗菌肽Lausporin-1设计衍生肽以优化其抗“ESKAPE”病原菌活性; Analogues Designed from Scorpion-Derived Peptide Lausporin-1 Exhibit Improved Antimicrobial Activity Against ‘ESKAPE’ Pathogens. [J].湖北医药学院学报,2021,40(05):441-445+453. DOI:10.13819/j.issn.2096-708X.2021.05.001. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37236

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