Peptide Database

Peptide NameInterleukin-10

Function Ontology

Antimicrobial ▸ Antibacterial

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length160 amino acids

Chemical FormulaC826H1308N228O242S14

DescriptionStandard

        SRGQYSREDNNCTHFPVGQSHMLLELRTAFSQVKTFFQTKDQLDNILLTDSLMQDFKGYLGCQALSEMIQFYLVEVMPQAEKHGPEIKEHLNSLGEKLKTLRMRLRRCHRFLPCENKSKAVEQVKSDFNKLQDQGVYKAMNEFDIFINCIEAYMMIKMKS
    

Molecular Weight18753.51 Da

Isoelectric Point (pI)8.24

Net Charge (pH 7.0)1.87

Net Charge (pH 7.4) 1.28

Charge Density (pH 7.0) 0.0117

GRAVY Index-0.50

Hydrophobic Moment 0.65

Boman Index-0.09

Instability Index50.66

Aliphatic Index 74.94

Aromaticity 0.0938

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7700.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7690.57

LogP -71.35

H-bond Donors 266.0

H-bond Acceptors 263.0

Rotatable Bonds 650.0

Heavy Atoms 1310.0

Ring Count 24.0

Amide Bonds 179.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0316357 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyIL-10 family

Tax ID10090; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-108; 62-114

Bio-Activity Profile

Function

Cytokine Growth factor IL-10 family Antibacterial Growth factor signaling Host defense