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MYP_162990
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Basic Information
Pea-FMRFa-24
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
16 amino acids
C86H140N26O25S
Standard
Sequence
RALDQNLLVDEHLMRF
Physicochemical Analysis
1970.26 Da
5.38
-1.15
-1.40
-0.0717
-0.24
0.28
-0.12
-9.44
121.88
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
850.38
-6.03
29.0
26.0
67.0
138.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046782 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
FMRFamide related peptide
6978
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
PMID15355317 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15355317/
RECORD: Rec_0236228 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0243533 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Pea-FMRFa
6978
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Neuromodulator ACE inhibitory
Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
PaperUnique accumulation of neuropeptides in an insect: FMRFamide-related peptides in the cockroach, Periplaneta americana PMID15355317 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15355317/