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MYP_162966
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Basic Information
Gramicidin S analog 8
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
PXVXXXFPXXXLXF
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000447 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,5,6,9,10,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 49775
16.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0024726 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,5,6,9,10,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 29212
16.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0078271 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,5,6,9,10,11,13
Bio-Activity Profile
Hemolytic
human red blood cells
100 % hemolysis at 31.3 μM
Hemolysis
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0129026 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,5,6,9,10,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus N229-T034-PVL-
16.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0278993 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,5,6,9,10,11,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus USA 300-1110301146 PVL+
16.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
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